THIRD-PARTY LABS

Micro-dosing involves taking very small doses of mushrooms. ​ Micro-dosing is often used for its potential therapeutic and personal growth benefits. Many people who microdose report improved mood, creativity, and productivity, as well as a greater sense of connection to themselves and others.* ​ However, the scientific research on the benefits of microdosing is still in its early stages, and much more research is needed to fully understand the potential benefits and risks of this practice. Despite the lack of scientific consensus, interest in micro-dosing continues to grow.*

1. To schedule a Mushroom Micro-Dose Consult appointment, you must be a legal resident of Colorado. 2. Patients must be aged 21 or over. 3. All consult appointments include a free supply of capsules.

Your online consult includes a free supply of capsules that will be shipped to you after your appointment. Please note, we are not responsible for lost or stolen packages, and legally can not replace any Mushroom Capsule packages.

As with taking psychedelics in larger doses, micro-dosing isn’t for everyone, but following best practices ensures that you’ll figure that out.* If micro-dosing is for you, it’s important that you have the support you need to do it properly, especially if you have a diagnosed mental health condition or are on drugs that you think could be contraindicated with psychedelics.* The biggest mistake people make when micro-dosing is that they’re impatient and simply give up. Like with any change you make to your life—exercising, getting up earlier, changing your diet—you likely won’t figure out what works best for you immediately.* Everybody is different, and the most important thing is that you stick with a certain protocol, dose, or substance long enough to figure out if it works for you before changing or stopping. Consistency is key—so is journaling so you can really notice what’s making a difference for you. We can give you the tools, but if you want to be successful, you must use them.*

Follow-up appointments can be booked every 3 months, or as needed. To book a follow-up appointment, simply visit Holos Health.

People often use the words “cannabis” and “marijuana” interchangeably, but they don’t mean exactly the same thing.* The word “cannabis” refers to all products derived from the plant Cannabis sativa.* The cannabis plant contains about 540 chemical substances.* The word “marijuana” refers to parts of (or products from) the plant Cannabis sativa that contain substantial amounts of tetrahydrocannabinol (THC). THC is the substance that’s primarily responsible for the effects of marijuana on a person’s mental state.* Some cannabis plants contain very little THC. Under U.S. law, these plants are considered “industrial hemp” rather than marijuana.*

Cannabinoids are a group of substances found in the cannabis plant. The main cannabinoids people are most familiar with are THC and cannabidiol (CBD).* Besides THC and CBD, more than 100 other cannabinoids have been identified, such as: CBDA, CBG, CBGA, CBDV, and CBN.* Dr. Cohen has been practicing cannabinoid therapy at his medical practice Holos Health, for over a decade and has identified other cannabinoids (beyond CBD) for supporting various needs.*

Cannabinoids produce their effects by interacting with specific receptors, located within different parts of the central nervous system. Simply put, cannabinoids regulate how cells communicate—how they send, receive, or process messages.

The FDA has not approved the cannabis plant for any medical use. However, the FDA has approved several drugs that contain individual cannabinoids. Epidiolex, which contains a purified form of CBD derived from cannabis, was approved for the treatment of seizures associated with Lennox-Gastaut Syndrome or Dravet Syndrome, two rare and severe forms of epilepsy. Marinol and Syndros, which contain Dronabinol (synthetic THC), and Cesamet, which contains Nabilone (a synthetic substance similar to THC), are approved by the FDA. Dronabinol and Nabilone are used to treat nausea and vomiting caused by cancer chemotherapy. Dronabinol is also used to treat loss of appetite and weight loss in people with HIV/AIDS.

The Endocannabinoid System is widely distributed throughout the body including the brain, modulating many functions, and its activity may be modified by exogenous cannabinoids.* CB1 and CB2 receptors primarily serve as the binding sites for endocannabinoids as well as for phytocannabinoids.* However, the Cannabis sativa plant is not a single compound product but is known for its complicated molecular profile, producing a plethora of phytocannabinoids alongside a vast array of terpenes.* Thus, the “Entourage Effect” is a theory that suggests there is a synergistic effect when there is a Full Spectrum of naturally-occurring compounds present (i.e. various cannabinoids, terpenes, and other compounds). Whereas, products that are either Broad Spectrum or Isolates may not have the same effect.*